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Genome-Wide DNA Methylation Analysis and Epigenetic Variations Associated with Congenital Aortic Valve Stenosis (AVS)

Congenital heart defect (CHD) is the most common cause of death from congenital anomaly. Among several candidate epigenetic mechanisms, DNA methylation may play an important role in the etiology of CHDs. We conducted a genome-wide DNA methylation analysis using an Illumina Infinium 450k human methyl...

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Detalles Bibliográficos
Autores principales: Radhakrishna, Uppala, Albayrak, Samet, Alpay-Savasan, Zeynep, Zeb, Amna, Turkoglu, Onur, Sobolewski, Paul, Bahado-Singh, Ray O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859473/
https://www.ncbi.nlm.nih.gov/pubmed/27152866
http://dx.doi.org/10.1371/journal.pone.0154010