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EGFR Activation Leads to Cell Death Independent of PI3K/AKT/mTOR in an AD293 Cell Line

The Epidermal Growth Factor Receptor (EGFR) and its mutations contribute in various ways to tumorigenesis and biology of human cancers. They are associated with tumor proliferation, progression, drug resistance and the process of apoptosis. There are also reports that overexpression and activation o...

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Detalles Bibliográficos
Autores principales: Treda, Cezary, Popeda, Marta, Ksiazkiewicz, Magdalena, Grzela, Dawid P., Walczak, Maciej P., Banaszczyk, Mateusz, Peciak, Joanna, Stoczynska-Fidelus, Ewelina, Rieske, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859505/
https://www.ncbi.nlm.nih.gov/pubmed/27153109
http://dx.doi.org/10.1371/journal.pone.0155230