PABPN1-Dependent mRNA Processing Induces Muscle Wasting

Poly(A) Binding Protein Nuclear 1 (PABPN1) is a multifunctional regulator of mRNA processing, and its expression levels specifically decline in aging muscles. An expansion mutation in PABPN1 is the genetic cause of oculopharyngeal muscle dystrophy (OPMD), a late onset and rare myopathy. Moreover, re...

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Detalles Bibliográficos
Autores principales: Riaz, Muhammad, Raz, Yotam, van Putten, Maaike, Paniagua-Soriano, Guillem, Krom, Yvonne D., Florea, Bogdan I., Raz, Vered
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859507/
https://www.ncbi.nlm.nih.gov/pubmed/27152426
http://dx.doi.org/10.1371/journal.pgen.1006031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859507/
https://www.ncbi.nlm.nih.gov/pubmed/27152426
http://dx.doi.org/10.1371/journal.pgen.1006031

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