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Investigating the Influence of Ribavirin on Human Respiratory Syncytial Virus RNA Synthesis by Using a High-Resolution Transcriptome Sequencing Approach

Human respiratory syncytial virus (HRSV) is a major cause of serious respiratory tract infection. Treatment options include administration of ribavirin, a purine analog, although the mechanism of its anti-HRSV activity is unknown. We used transcriptome sequencing (RNA-seq) to investigate the genome...

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Detalles Bibliográficos
Autores principales: Aljabr, Waleed, Touzelet, Olivier, Pollakis, Georgios, Wu, Weining, Munday, Diane C., Hughes, Margaret, Hertz-Fowler, Christiane, Kenny, John, Fearns, Rachel, Barr, John N., Matthews, David A., Hiscox, Julian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859727/
https://www.ncbi.nlm.nih.gov/pubmed/26656699
http://dx.doi.org/10.1128/JVI.02349-15