Manganese superoxide dismutase deficiency triggers mitochondrial uncoupling and the Warburg effect

Manganese superoxide dismutase (MnSOD) is a mitochondrially localized primary antioxidant enzyme, known to be essential for the survival of aerobic life and to play important roles in tumorigenesis. Here, we show that MnSOD deficiency in skin tissues of MnSOD-heterozygous knockout (Sod2(+/−)) mice l...

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Detalles Bibliográficos
Autores principales: Xu, Yong, Miriyala, Sumitra, Fang, Fang, Bakthavatchalu, Vasudevan, Noel, Teresa, Schnell, David, Wang, Chi, St Clair, William H, St Clair, Daret K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859767/
https://www.ncbi.nlm.nih.gov/pubmed/25362851
http://dx.doi.org/10.1038/onc.2014.355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859767/
https://www.ncbi.nlm.nih.gov/pubmed/25362851
http://dx.doi.org/10.1038/onc.2014.355

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