Liver X receptor-β improves autism symptoms via downregulation of β-amyloid expression in cortical neurons

BACKGROUND: We study the effect of liver X receptor β (LXRβ) on β-amyloid (Aβ) peptide generation and autism behaviors by conducting an animal experiment. METHODS: In autistic mice treated with LXRβ agonist T0901317, enzyme linked immunosorbent assay was used to measure Aβ in brain tissue homogenate...

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Detalles Bibliográficos
Autores principales: Zhang, Ji-Xiang, Zhang, Jun, Li, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859958/
https://www.ncbi.nlm.nih.gov/pubmed/27154582
http://dx.doi.org/10.1186/s13052-016-0249-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859958/
https://www.ncbi.nlm.nih.gov/pubmed/27154582
http://dx.doi.org/10.1186/s13052-016-0249-4

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