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Liver X receptor-β improves autism symptoms via downregulation of β-amyloid expression in cortical neurons

BACKGROUND: We study the effect of liver X receptor β (LXRβ) on β-amyloid (Aβ) peptide generation and autism behaviors by conducting an animal experiment. METHODS: In autistic mice treated with LXRβ agonist T0901317, enzyme linked immunosorbent assay was used to measure Aβ in brain tissue homogenate...

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Detalles Bibliográficos
Autores principales:	Zhang, Ji-Xiang, Zhang, Jun, Li, Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859958/ https://www.ncbi.nlm.nih.gov/pubmed/27154582 http://dx.doi.org/10.1186/s13052-016-0249-4

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