Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis

Bacteroides fragilis is the leading cause of anaerobic bacteremia and sepsis (1). Enterotoxigenic strains producing B. fragilis toxin (BFT, fragilysin) contribute to colitis (2) and intestinal malignancy (3), yet are also isolated in bloodstream infection (4,5). It is not known whether these strains...

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Detalles Bibliográficos
Autores principales: Choi, Vivian M., Herrou, Julien, Hecht, Aaron L., Teoh, Wei Ping, Turner, Jerrold R., Crosson, Sean, Wardenburg, Juliane Bubeck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860040/
https://www.ncbi.nlm.nih.gov/pubmed/27089515
http://dx.doi.org/10.1038/nm.4077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860040/
https://www.ncbi.nlm.nih.gov/pubmed/27089515
http://dx.doi.org/10.1038/nm.4077

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