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Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis
Bacteroides fragilis is the leading cause of anaerobic bacteremia and sepsis (1). Enterotoxigenic strains producing B. fragilis toxin (BFT, fragilysin) contribute to colitis (2) and intestinal malignancy (3), yet are also isolated in bloodstream infection (4,5). It is not known whether these strains...
Autores principales: | Choi, Vivian M., Herrou, Julien, Hecht, Aaron L., Teoh, Wei Ping, Turner, Jerrold R., Crosson, Sean, Wardenburg, Juliane Bubeck |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860040/ https://www.ncbi.nlm.nih.gov/pubmed/27089515 http://dx.doi.org/10.1038/nm.4077 |
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