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Inflammatory signaling in human Tuberculosis granulomas is spatially organized

Granulomas are the pathological hallmark of tuberculosis (TB). However, their function and mechanisms of formation remain poorly understood. To understand the role of granulomas in TB, we analyzed the proteomes of granulomas from subjects with tuberculosis in an unbiased fashion. Using laser capture...

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Detalles Bibliográficos
Autores principales: Marakalala, Mohlopheni J., Raju, Ravikiran M., Sharma, Kirti, Zhang, Yanjia J., Eugenin, Eliseo A., Prideaux, Brendan, Daudelin, Isaac B., Chen, Pei-Yu, Booty, Matthew G., Kim, Jin Hee, Eum, Seok Yong, Via, Laura E., Behar, Samuel M., Barry, Clifton E., Mann, Matthias, Dartois, Véronique, Rubin, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860068/
https://www.ncbi.nlm.nih.gov/pubmed/27043495
http://dx.doi.org/10.1038/nm.4073