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Inflammatory signaling in human Tuberculosis granulomas is spatially organized
Granulomas are the pathological hallmark of tuberculosis (TB). However, their function and mechanisms of formation remain poorly understood. To understand the role of granulomas in TB, we analyzed the proteomes of granulomas from subjects with tuberculosis in an unbiased fashion. Using laser capture...
Autores principales: | Marakalala, Mohlopheni J., Raju, Ravikiran M., Sharma, Kirti, Zhang, Yanjia J., Eugenin, Eliseo A., Prideaux, Brendan, Daudelin, Isaac B., Chen, Pei-Yu, Booty, Matthew G., Kim, Jin Hee, Eum, Seok Yong, Via, Laura E., Behar, Samuel M., Barry, Clifton E., Mann, Matthias, Dartois, Véronique, Rubin, Eric J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860068/ https://www.ncbi.nlm.nih.gov/pubmed/27043495 http://dx.doi.org/10.1038/nm.4073 |
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