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Hair cell stereociliary bundle regeneration by espin gene transduction after aminoglycoside damage and hair cell induction by Notch inhibition

Once inner ear hair cells (HCs) are damaged by drugs, noise or aging, their apical structures including the stereociliary arrays are frequently the first cellular feature to be lost. While this can be followed by progressive loss of HC somata, a significant number of HC bodies often remain even afte...

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Detalles Bibliográficos
Autores principales: Taura, Akiko, Taura, Kojiro, Koyama, Yukinori, Yamamoto, Norio, Nakagawa, Takayuki, Ito, Juichi, Ryan, Allen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860107/
https://www.ncbi.nlm.nih.gov/pubmed/26886463
http://dx.doi.org/10.1038/gt.2016.12