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Impact of slow K(+) currents on spike generation can be described by an adaptive threshold model
A neuron that is stimulated by rectangular current injections initially responds with a high firing rate, followed by a decrease in the firing rate. This phenomenon is called spike-frequency adaptation and is usually mediated by slow K(+) currents, such as the M-type K(+) current (I(M)) or the Ca(2+...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860204/ https://www.ncbi.nlm.nih.gov/pubmed/27085337 http://dx.doi.org/10.1007/s10827-016-0601-0 |