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Impact of slow K(+) currents on spike generation can be described by an adaptive threshold model

A neuron that is stimulated by rectangular current injections initially responds with a high firing rate, followed by a decrease in the firing rate. This phenomenon is called spike-frequency adaptation and is usually mediated by slow K(+) currents, such as the M-type K(+) current (I(M)) or the Ca(2+...

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Detalles Bibliográficos
Autores principales: Kobayashi, Ryota, Kitano, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860204/
https://www.ncbi.nlm.nih.gov/pubmed/27085337
http://dx.doi.org/10.1007/s10827-016-0601-0