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The Protective Effect of Beraprost Sodium on Diabetic Nephropathy by Inhibiting Inflammation and p38 MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Rats

Background. p38 mitogen-activated protein kinase (MAPK) plays a crucial role in regulating signaling pathways implicated in inflammatory processes leading to diabetic nephropathy (DN). This study aimed to examine p38 MAPK activation in DN and determine whether beraprost sodium (BPS) ameliorates DN b...

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Detalles Bibliográficos
Autores principales: Peng, Li, Li, Jie, Xu, Yixing, Wang, Yangtian, Du, Hong, Shao, Jiaqing, Liu, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860249/
https://www.ncbi.nlm.nih.gov/pubmed/27212945
http://dx.doi.org/10.1155/2016/1690474