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Crystal structure of the 3C protease from Southern African Territories type 2 foot-and-mouth disease virus

The replication of foot-and-mouth disease virus (FMDV) is dependent on the virus-encoded 3C protease (3C(pro)). As in other picornaviruses, 3C(pro) performs most of the proteolytic processing of the polyprotein expressed from the large open reading frame in the RNA genome of the virus. Previous work...

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Detalles Bibliográficos
Autores principales: Yang, Jingjie, Leen, Eoin N., Maree, Francois F., Curry, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860321/
https://www.ncbi.nlm.nih.gov/pubmed/27168976
http://dx.doi.org/10.7717/peerj.1964