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Oleanolic acid induced autophagic cell death in hepatocellular carcinoma cells via PI3K/Akt/mTOR and ROS-dependent pathway

Oleanolic acid (OA) has a wide variety of bioactivities such as hepatoprotective, anti-inflammatory and anti-cancer activity and is used for medicinal purposes in many Asian countries. In the present study, the effect of OA on induction of autophagy in human hepatocellular carcinoma HepG2 and SMC772...

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Detalles Bibliográficos
Autores principales: Shi, Yang, Song, Qingwei, Hu, Dianhe, Zhuang, Xiaohu, Yu, Shengcai, Teng, Dacai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860365/
https://www.ncbi.nlm.nih.gov/pubmed/27162477
http://dx.doi.org/10.4196/kjpp.2016.20.3.237