Soluble RAGE Treatment Delays Progression of Amyotrophic Lateral Sclerosis in SOD1 Mice

The etiology of amyotrophic lateral sclerosis (ALS), a fatal motor neuron disorder characterized by progressive muscle weakness and spasticity, remains largely unknown. Approximately 5–10% of cases are familial, and of those, 15–20% are associated with mutations in the gene encoding Cu/Zn superoxide...

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Detalles Bibliográficos
Autores principales: Juranek, Judyta K., Daffu, Gurdip K., Geddis, Matthew S., Li, Huilin, Rosario, Rosa, Kaplan, Benjamin J., Kelly, Lauren, Schmidt, Ann Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860390/
https://www.ncbi.nlm.nih.gov/pubmed/27242430
http://dx.doi.org/10.3389/fncel.2016.00117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860390/
https://www.ncbi.nlm.nih.gov/pubmed/27242430
http://dx.doi.org/10.3389/fncel.2016.00117

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