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NADPH Oxidase-Derived ROS Induced by Chronic Intermittent Hypoxia Mediates Hypersensitivity of Lung Vagal C Fibers in Rats

Obstructive sleep apnea (OSA), manifested by exposure to chronic intermittent hypoxia (CIH) and excess production of reactive oxygen species (ROS) in the airways, is associated with hyperreactive airway diseases. ROS, particularly when created by NADPH oxidase, are known to sensitize lung vagal C fi...

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Detalles Bibliográficos
Autores principales: Yang, Chang-Huan, Zhuang, Wei-Ling, Shen, Yan-Jhih, Lai, Ching Jung, Kou, Yu Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860401/
https://www.ncbi.nlm.nih.gov/pubmed/27242540
http://dx.doi.org/10.3389/fphys.2016.00166