Phosphorylation Modulates Catalytic Activity of Mycobacterial Sirtuins

Sirtuins are NAD(+)-dependent deacetylases involved in the regulation of diverse cellular processes and are conserved throughout phylogeny. Here we report about in vitro transphosphorylation of the only NAD(+)-dependent deacetylase (mDAC) present in the genome of Mycobacterium tuberculosis by eukary...

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Detalles Bibliográficos
Autores principales: Yadav, Ghanshyam S., Ravala, Sandeep K., Malhotra, Neha, Chakraborti, Pradip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860497/
https://www.ncbi.nlm.nih.gov/pubmed/27242704
http://dx.doi.org/10.3389/fmicb.2016.00677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860497/
https://www.ncbi.nlm.nih.gov/pubmed/27242704
http://dx.doi.org/10.3389/fmicb.2016.00677

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