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Regulation of the Telomerase Reverse Transcriptase Subunit through Epigenetic Mechanisms
Chromosome-shortening is characteristic of normal cells, and is known as the end replication problem. Telomerase is the enzyme responsible for extending the ends of the chromosomes in de novo synthesis, and occurs in germ cells as well as most malignant cancers. There are three subunits of telomeras...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860561/ https://www.ncbi.nlm.nih.gov/pubmed/27242892 http://dx.doi.org/10.3389/fgene.2016.00083 |