Detection and Quantification of CWD Prions in Fixed Paraffin Embedded Tissues by Real-Time Quaking-Induced Conversion

Traditional diagnostic detection of chronic wasting disease (CWD) relies on immunodetection of misfolded CWD prion protein (PrP(CWD)) by western blotting, ELISA, or immunohistochemistry (IHC). These techniques require separate sample collections (frozen and fixed) which may result in discrepancies d...

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Detalles Bibliográficos
Autores principales: Hoover, Clare E., Davenport, Kristen A., Henderson, Davin M., Pulscher, Laura A., Mathiason, Candace K., Zabel, Mark D., Hoover, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860571/
https://www.ncbi.nlm.nih.gov/pubmed/27157060
http://dx.doi.org/10.1038/srep25098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860571/
https://www.ncbi.nlm.nih.gov/pubmed/27157060
http://dx.doi.org/10.1038/srep25098

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