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Activated Stat5 trafficking Via Endothelial Cell-derived Extracellular Vesicles Controls IL-3 Pro-angiogenic Paracrine Action

Soluble factors and cell-derived extracellular vesicles (EVs) control vascular cell fate during inflammation. The present study investigates the impact of Interleukin 3 (IL-3) on EV release by endothelial cells (ECs), the mechanisms involved in EV release and paracrine actions. We found that IL-3 in...

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Detalles Bibliográficos
Autores principales: Lombardo, Giusy, Dentelli, Patrizia, Togliatto, Gabriele, Rosso, Arturo, Gili, Maddalena, Gallo, Sara, Deregibus, Maria Chiara, Camussi, Giovanni, Brizzi, Maria Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860593/
https://www.ncbi.nlm.nih.gov/pubmed/27157262
http://dx.doi.org/10.1038/srep25689