A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways

Embryonic stem (ES) cells share markers with undifferentiated primordial germ cells (PGCs). Here, we discovered that a cellular state with some molecular markers of male gonocyte induction, including a G1/S phase arrest and upregulation of specific genes such as Nanos2, Tdrd1, Ddx4, Zbtb16 and Plk1s...

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Detalles Bibliográficos
Autores principales: Moshfegh, Cameron, Aires, Lina, Kisielow, Malgorzata, Vogel, Viola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860597/
https://www.ncbi.nlm.nih.gov/pubmed/27157261
http://dx.doi.org/10.1038/srep25104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860597/
https://www.ncbi.nlm.nih.gov/pubmed/27157261
http://dx.doi.org/10.1038/srep25104

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