Loss of the 14-3-3σ is essential for LASP1-mediated colorectal cancer progression via activating PI3K/AKT signaling pathway

LIM and SH3 protein 1 (LASP1) can promote colorectal cancer (CRC) progression and metastasis, but the direct evidence that elucidates the molecular mechanism remains unclear. Here, our proteomic data showed that LASP1 interacted with 14-3-3σ and decreased the expression of 14-3-3σ in CRC. Deletion o...

Descripción completa

Detalles Bibliográficos
Autores principales: Shao, Ziyun, Cai, Yanjun, Xu, Lijun, Yao, Xueqing, Shi, Jiaolong, Zhang, Feifei, Luo, Yuhao, Zheng, Kehong, Liu, Jian, Deng, Fengliu, Li, Rui, Zhang, Lanzhi, Wang, Hui, Li, Mingyi, Ding, Yanqing, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860602/
https://www.ncbi.nlm.nih.gov/pubmed/27156963
http://dx.doi.org/10.1038/srep25631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860602/
https://www.ncbi.nlm.nih.gov/pubmed/27156963
http://dx.doi.org/10.1038/srep25631

Ejemplares similares