N-hypermannose glycosylation disruption enhances recombinant protein production by regulating secretory pathway and cell wall integrity in Saccharomyces cerevisiae

Saccharomyces cerevisiae is a robust host for heterologous protein expression. The efficient expression of cellulases in S. cerevisiae is important for the consolidated bioprocess that directly converts lignocellulose into valuable products. However, heterologous proteins are often N-hyperglycosylat...

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Detalles Bibliográficos
Autores principales: Tang, Hongting, Wang, Shenghuan, Wang, Jiajing, Song, Meihui, Xu, Mengyang, Zhang, Mengying, Shen, Yu, Hou, Jin, Bao, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860636/
https://www.ncbi.nlm.nih.gov/pubmed/27156860
http://dx.doi.org/10.1038/srep25654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860636/
https://www.ncbi.nlm.nih.gov/pubmed/27156860
http://dx.doi.org/10.1038/srep25654

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