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Functional Divergence in Teleost Cardiac Troponin Paralogs Guides Variation in the Interaction of TnI Switch Region with TnC

Gene duplication results in extra copies of genes that must coevolve with their interacting partners in multimeric protein complexes. The cardiac troponin (Tn) complex, containing TnC, TnI, and TnT, forms a distinct functional unit critical for the regulation of cardiac muscle contraction. In teleos...

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Detalles Bibliográficos
Autores principales: Genge, Christine E., Stevens, Charles M., Davidson, William S., Singh, Gurpreet, Peter Tieleman, D., Tibbits, Glen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860682/
https://www.ncbi.nlm.nih.gov/pubmed/26979795
http://dx.doi.org/10.1093/gbe/evw044