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Functional Divergence in Teleost Cardiac Troponin Paralogs Guides Variation in the Interaction of TnI Switch Region with TnC
Gene duplication results in extra copies of genes that must coevolve with their interacting partners in multimeric protein complexes. The cardiac troponin (Tn) complex, containing TnC, TnI, and TnT, forms a distinct functional unit critical for the regulation of cardiac muscle contraction. In teleos...
Autores principales: | Genge, Christine E., Stevens, Charles M., Davidson, William S., Singh, Gurpreet, Peter Tieleman, D., Tibbits, Glen F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860682/ https://www.ncbi.nlm.nih.gov/pubmed/26979795 http://dx.doi.org/10.1093/gbe/evw044 |
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