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Genome Hotspots for Nucleotide Substitutions and the Evolution of Influenza A (H1N1) Human Strains

In recent years a number of studies have brought attention to the role of positive selection during the evolution of antigenic escape by influenza strains. Particularly, the identification of positively selected sites within antigenic domains of viral surface proteins has been used to suggest that t...

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Detalles Bibliográficos
Autores principales: Civetta, Alberto, Ostapchuk, David Cecil Murphy, Nwali, Basil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860693/
https://www.ncbi.nlm.nih.gov/pubmed/26988249
http://dx.doi.org/10.1093/gbe/evw061