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Rapidly generating knockout mice from H19-Igf2 engineered androgenetic haploid embryonic stem cells
Haploid mammalian embryonic stem cells (ESCs) hold great promise for functional genetic studies and assisted reproduction. Recently, rodent androgenetic haploid ESCs (AG-haESCs) were generated from androgenetic blastocysts and functioned like sperm to produce viable offspring via the intracytoplasmi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860787/ https://www.ncbi.nlm.nih.gov/pubmed/27462429 http://dx.doi.org/10.1038/celldisc.2015.31 |