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Rapidly generating knockout mice from H19-Igf2 engineered androgenetic haploid embryonic stem cells

Haploid mammalian embryonic stem cells (ESCs) hold great promise for functional genetic studies and assisted reproduction. Recently, rodent androgenetic haploid ESCs (AG-haESCs) were generated from androgenetic blastocysts and functioned like sperm to produce viable offspring via the intracytoplasmi...

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Detalles Bibliográficos
Autores principales: Zhang, Meili, Liu, Yufang, Liu, Guang, Li, Xin, Jia, Yuyan, Sun, Lihong, Wang, Liu, Zhou, Qi, Huang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860787/
https://www.ncbi.nlm.nih.gov/pubmed/27462429
http://dx.doi.org/10.1038/celldisc.2015.31