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Uniparental disomy of the entire X chromosome in Turner syndrome patient-specific induced pluripotent stem cells

The human induced pluripotent stem cell (iPSC) technique promises to provide an unlimited, reliable source of genetically matched pluripotent cells for personalized therapy and disease modeling. Recently, it is observed that cells with ring chromosomes 13 or 17 autonomously correct the defects via c...

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Detalles Bibliográficos
Autores principales: Luo, Yumei, Zhu, Detu, Du, Rong, Gong, Yu, Xie, Chun, Xu, Xiangye, Fan, Yong, Yu, Bolan, Sun, Xiaofang, Chen, Yaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860828/
https://www.ncbi.nlm.nih.gov/pubmed/27462421
http://dx.doi.org/10.1038/celldisc.2015.22