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ALG-2 activates the MVB sorting function of ALIX through relieving its intramolecular interaction
The modular adaptor protein ALIX is critically involved in endosomal sorting complexes required for transport (ESCRT)-mediated multivesicular body (MVB) sorting of activated epidermal growth factor receptor (EGFR); however, ALIX contains a default intramolecular interaction that renders ALIX unable...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860835/ https://www.ncbi.nlm.nih.gov/pubmed/27462417 http://dx.doi.org/10.1038/celldisc.2015.18 |