ALG-2 activates the MVB sorting function of ALIX through relieving its intramolecular interaction

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The modular adaptor protein ALIX is critically involved in endosomal sorting complexes required for transport (ESCRT)-mediated multivesicular body (MVB) sorting of activated epidermal growth factor receptor (EGFR); however, ALIX contains a default intramolecular interaction that renders ALIX unable...

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Detalles Bibliográficos
Autores principales: Sun, Sheng, Zhou, Xi, Corvera, Joe, Gallick, Gary E, Lin, Sue-Hwa, Kuang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860835/
https://www.ncbi.nlm.nih.gov/pubmed/27462417
http://dx.doi.org/10.1038/celldisc.2015.18

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