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Identification of putative novel O-glycosylations in the NK killer receptor Ncr1 essential for its activity

Natural killer (NK) cells kill tumor and virus-infected cells using activating NK cell receptors. One of the major NK-activating receptors is NKp46 and its mouse ortholog Ncr1. NKp46/Ncr1 is expressed exclusively on NK cells and on a subset of innate lymphoid cells. NKp46/Ncr1 was shown to be involv...

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Detalles Bibliográficos
Autores principales: Glasner, Ariella, Roth, Ziv, Varvak, Alexander, Miletic, Antonija, Isaacson, Batya, Bar-On, Yotam, Jonjic, Stipan, Khalaila, Isam, Mandelboim, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860851/
https://www.ncbi.nlm.nih.gov/pubmed/27462433
http://dx.doi.org/10.1038/celldisc.2015.36