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Histone Deacetylase Inhibitors Delivery using Nanoparticles with Intrinsic Passive Tumor Targeting Properties for Tumor Therapy

Fast clearance, metabolism and systemic toxicity are major limits for the clinical use of anti-cancer drugs. Histone deacetylase inhibitors (HDACi) present these defects despite displaying promising anti-tumor properties on tumor cells in vitro and in in vivo model of cancers. Specific delivery of a...

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Detalles Bibliográficos
Autores principales: el Bahhaj, Fatima, Denis, Iza, Pichavant, Loic, Delatouche, Régis, Collette, Floraine, Linot, Camille, Pouliquen, Daniel, Grégoire, Marc, Héroguez, Valérie, Blanquart, Christophe, Bertrand, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860888/
https://www.ncbi.nlm.nih.gov/pubmed/27162550
http://dx.doi.org/10.7150/thno.13725