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Imaging and Selective Elimination of Glioblastoma Stem Cells with Theranostic Near-Infrared-Labeled CD133-Specific Antibodies

Near-infrared photoimmunotherapy (NIR-PIT), which employs monoclonal antibody (mAb)-phototoxic phthalocyanine dye IR700 conjugates, permits the specific, image-guided and spatiotemporally controlled elimination of tumor cells. Here, we report the highly efficient NIR-PIT of human tumor xenografts in...

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Detalles Bibliográficos
Autores principales: Jing, Hua, Weidensteiner, Claudia, Reichardt, Wilfried, Gaedicke, Simone, Zhu, Xuekai, Grosu, Anca-Ligia, Kobayashi, Hisataka, Niedermann, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860894/
https://www.ncbi.nlm.nih.gov/pubmed/27162556
http://dx.doi.org/10.7150/thno.12890