Reductive carboxylation supports redox homeostasis during anchorage-independent growth

Epithelial cells receive growth and survival stimuli through their attachment to an extracellular matrix (ECM)(1). Overcoming the addiction to ECM-induced signals is required for anchorage-independent growth, a property of most malignant cells(2). Detachment from ECM is associated with enhanced reac...

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Detalles Bibliográficos
Autores principales: Jiang, Lei, Shestov, Alexander A., Swain, Pamela, Yang, Chendong, Parker, Seth J., Wang, Qiong A., Terada, Lance S., Adams, Nicholas D., McCabe, Michael T., Pietrak, Beth, Schmidt, Stan, Metallo, Christian M., Dranka, Brian P., Schwartz, Benjamin, DeBerardinis, Ralph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860952/
https://www.ncbi.nlm.nih.gov/pubmed/27049945
http://dx.doi.org/10.1038/nature17393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860952/
https://www.ncbi.nlm.nih.gov/pubmed/27049945
http://dx.doi.org/10.1038/nature17393

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