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Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded

Non-receptor tyrosine kinase activated cdc42 kinase was reported to participate in several types of cancers in mammals. It is also believed to have an anti-apoptotic function in Drosophila. Here, we report the identification of Drosophila activated cdc42 kinase as a growth promoter and a novel Hippo...

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Detalles Bibliográficos
Autores principales: Hu, Lianxin, Xu, Jiajun, Yin, Meng-Xin, Zhang, Liguo, Lu, Yi, Wu, Wenqing, Xue, Zhaoyu, Ho, Margaret S, Gao, Guanjun, Zhao, Yun, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860957/
https://www.ncbi.nlm.nih.gov/pubmed/27462444
http://dx.doi.org/10.1038/celldisc.2015.47