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Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded
Non-receptor tyrosine kinase activated cdc42 kinase was reported to participate in several types of cancers in mammals. It is also believed to have an anti-apoptotic function in Drosophila. Here, we report the identification of Drosophila activated cdc42 kinase as a growth promoter and a novel Hippo...
Autores principales: | Hu, Lianxin, Xu, Jiajun, Yin, Meng-Xin, Zhang, Liguo, Lu, Yi, Wu, Wenqing, Xue, Zhaoyu, Ho, Margaret S, Gao, Guanjun, Zhao, Yun, Zhang, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860957/ https://www.ncbi.nlm.nih.gov/pubmed/27462444 http://dx.doi.org/10.1038/celldisc.2015.47 |
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