TRIB2 regulates normal and stress-induced thymocyte proliferation

TRIB2, a serine/threonine pseudokinase identified as an oncogene, is expressed at high levels in the T-cell compartment of hematopoiesis. The proliferation of developing thymocytes is tightly controlled to prevent leukemic transformation of T cells. Here we examine Trib2 loss in murine hematopoiesis...

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Detalles Bibliográficos
Autores principales: Liang, Kai Ling, O’Connor, Caitriona, Veiga, J Pedro, McCarthy, Tommie V, Keeshan, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860960/
https://www.ncbi.nlm.nih.gov/pubmed/27462446
http://dx.doi.org/10.1038/celldisc.2015.50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860960/
https://www.ncbi.nlm.nih.gov/pubmed/27462446
http://dx.doi.org/10.1038/celldisc.2015.50

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