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Mapping gene regulatory circuitry of Pax6 during neurogenesis

Pax6 is a highly conserved transcription factor among vertebrates and is important in various aspects of the central nervous system development. However, the gene regulatory circuitry of Pax6 underlying these functions remains elusive. We find that Pax6 targets a large number of promoters in neural...

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Detalles Bibliográficos
Autores principales: Thakurela, Sudhir, Tiwari, Neha, Schick, Sandra, Garding, Angela, Ivanek, Robert, Berninger, Benedikt, Tiwari, Vijay K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860964/
https://www.ncbi.nlm.nih.gov/pubmed/27462442
http://dx.doi.org/10.1038/celldisc.2015.45