Temporal activation of XRCC1-mediated DNA repair is essential for muscle differentiation

Transient DNA strand break formation has been identified as an effective means to enhance gene expression in living cells. In the muscle lineage, cell differentiation is contingent upon the induction of caspase-mediated DNA strand breaks, which act to establish the terminal gene expression program....

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Detalles Bibliográficos
Autores principales: Al-Khalaf, Mohammad H, Blake, Leanne E, Larsen, Brian D, Bell, Ryan A, Brunette, Steve, Parks, Robin J, Rudnicki, Michael A, McKinnon, Peter J, Jeffrey Dilworth, F, Megeney, Lynn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860966/
https://www.ncbi.nlm.nih.gov/pubmed/27462438
http://dx.doi.org/10.1038/celldisc.2015.41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860966/
https://www.ncbi.nlm.nih.gov/pubmed/27462438
http://dx.doi.org/10.1038/celldisc.2015.41

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