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Direct Interaction between TalinB and Rap1 is necessary for adhesion of Dictyostelium cells

BACKGROUND: The small G-protein Rap1 is an important regulator of cellular adhesion in Dictyostelium, however so far the downstream signalling pathways for cell adhesion are not completely characterized. In mammalian cells talin is crucial for adhesion and Rap1 was shown to be a key regulator of tal...

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Detalles Bibliográficos
Autores principales: Plak, Katarzyna, Pots, Henderikus, Van Haastert, Peter J. M., Kortholt, Arjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861126/
https://www.ncbi.nlm.nih.gov/pubmed/26744136
http://dx.doi.org/10.1186/s12860-015-0078-0