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Maternal High-Fat Diet-Induced Loss of Fetal Oocytes Is Associated with Compromised Follicle Growth in Adult Rat Offspring

Maternal obesity predisposes offspring to metabolic and reproductive dysfunction. We have shown previously that female rat offspring born to mothers fed a high-fat (HF) diet throughout pregnancy and lactation enter puberty early and display aberrant reproductive cyclicity. The mechanisms driving thi...

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Detalles Bibliográficos
Autores principales: Tsoulis, Michael W., Chang, Pauline E., Moore, Caroline J., Chan, Kaitlyn A., Gohir, Wajiha, Petrik, James J., Vickers, Mark H., Connor, Kristin L., Sloboda, Deborah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for the Study of Reproduction, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861169/
https://www.ncbi.nlm.nih.gov/pubmed/26962114
http://dx.doi.org/10.1095/biolreprod.115.135004