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Oxidative Glial Cell Damage Associated with White Matter Lesions in the Aging Human Brain

White matter lesions (WML) are common in brain aging and are associated with dementia. We aimed to investigate whether oxidative DNA damage and occur in WML and in apparently normal white matter in cases with lesions. Tissue from WML and control white matter from brains with lesions (controls lesion...

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Detalles Bibliográficos
Autores principales: Al‐Mashhadi, Sufana, Simpson, Julie E., Heath, Paul R., Dickman, Mark, Forster, Gillian, Matthews, Fiona E., Brayne, Carol, Ince, Paul G., Wharton, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861214/
https://www.ncbi.nlm.nih.gov/pubmed/25311358
http://dx.doi.org/10.1111/bpa.12216