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Longitudinal copy number, whole exome and targeted deep sequencing of 'good risk' IGHV-mutated CLL patients with progressive disease

The biological features of IGHV-M chronic lymphocytic leukemia responsible for disease progression are still poorly understood. We undertook a longitudinal study close to diagnosis, pre-treatment and post relapse in 13 patients presenting with cMBL or Stage A disease and good-risk biomarkers (IGHV-M...

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Detalles Bibliográficos
Autores principales: Rose-Zerilli, M J J, Gibson, J, Wang, J, Tapper, W, Davis, Z, Parker, H, Larrayoz, M, McCarthy, H, Walewska, R, Forster, J, Gardiner, A, Steele, A J, Chelala, C, Ennis, S, Collins, A, Oakes, C C, Oscier, D G, Strefford, J C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861248/
https://www.ncbi.nlm.nih.gov/pubmed/26847028
http://dx.doi.org/10.1038/leu.2016.10