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Obesity Takes Its Toll on Visceral Pain: High-Fat Diet Induces Toll-Like Receptor 4-Dependent Visceral Hypersensitivity

Exposure to high-fat diet induces both, peripheral and central alterations in TLR4 expression. Moreover, functional TLR4 is required for the development of high-fat diet-induced obesity. Recently, central alterations in TLR4 expression have been associated with the modulation of visceral pain. Howev...

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Detalles Bibliográficos
Autores principales: Tramullas, Mónica, Finger, Beate C., Dinan, Timothy G., Cryan, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861320/
https://www.ncbi.nlm.nih.gov/pubmed/27159520
http://dx.doi.org/10.1371/journal.pone.0155367