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Obesity Takes Its Toll on Visceral Pain: High-Fat Diet Induces Toll-Like Receptor 4-Dependent Visceral Hypersensitivity
Exposure to high-fat diet induces both, peripheral and central alterations in TLR4 expression. Moreover, functional TLR4 is required for the development of high-fat diet-induced obesity. Recently, central alterations in TLR4 expression have been associated with the modulation of visceral pain. Howev...
Autores principales: | Tramullas, Mónica, Finger, Beate C., Dinan, Timothy G., Cryan, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861320/ https://www.ncbi.nlm.nih.gov/pubmed/27159520 http://dx.doi.org/10.1371/journal.pone.0155367 |
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