P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes

Type 1 diabetes (T1D) causes a range of skeletal problems, including reduced bone density and increased risk for bone fractures. However, mechanisms underlying skeletal complications in diabetes are still not well understood. We hypothesize that high glucose levels in T1D alters expression and funct...

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Detalles Bibliográficos
Autores principales: Seref-Ferlengez, Zeynep, Maung, Stephanie, Schaffler, Mitchell B., Spray, David C., Suadicani, Sylvia O., Thi, Mia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861344/
https://www.ncbi.nlm.nih.gov/pubmed/27159053
http://dx.doi.org/10.1371/journal.pone.0155107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861344/
https://www.ncbi.nlm.nih.gov/pubmed/27159053
http://dx.doi.org/10.1371/journal.pone.0155107

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