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Addressing the Role of Conformational Diversity in Protein Structure Prediction
Computational modeling of tertiary structures has become of standard use to study proteins that lack experimental characterization. Unfortunately, 3D structure prediction methods and model quality assessment programs often overlook that an ensemble of conformers in equilibrium populates the native s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861349/ https://www.ncbi.nlm.nih.gov/pubmed/27159429 http://dx.doi.org/10.1371/journal.pone.0154923 |