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Addressing the Role of Conformational Diversity in Protein Structure Prediction

Computational modeling of tertiary structures has become of standard use to study proteins that lack experimental characterization. Unfortunately, 3D structure prediction methods and model quality assessment programs often overlook that an ensemble of conformers in equilibrium populates the native s...

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Detalles Bibliográficos
Autores principales: Palopoli, Nicolas, Monzon, Alexander Miguel, Parisi, Gustavo, Fornasari, Maria Silvina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861349/
https://www.ncbi.nlm.nih.gov/pubmed/27159429
http://dx.doi.org/10.1371/journal.pone.0154923