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Extracellular and Luminal pH Regulation by Vacuolar H(+)-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes

Plasma membrane vacuolar H(+)-ATPase (V-ATPase) activity of tumor cells is a major factor in control of cytoplasmic and extracellular pH and metastatic potential, but the isoforms involved and the factors governing plasma membrane recruitment remain uncertain. Here, we examined expression, distribut...

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Detalles Bibliográficos
Autores principales: Smith, Gina A., Howell, Gareth J., Phillips, Clair, Muench, Stephen P., Ponnambalam, Sreenivasan, Harrison, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861423/
https://www.ncbi.nlm.nih.gov/pubmed/26912656
http://dx.doi.org/10.1074/jbc.M116.723395